STRANIX, Brent Richard,LAVALLEE, Jean-Francois,LEBERRE, Nicolas,PERRON, Valerie,HERBART, Dominik,MILOT, Guy,PANCHAL, Chandra J.
申请号：
ES07872067
公开号：
ES2628730T3
申请日:
2007.09.20
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A compound of formula I ** ** Formula or a pharmaceutically acceptable salt thereof, wherein Cx is selected from the group consisting of COOH and CONR5R6. wherein X and Y, identical or different, are selected from the group consisting of H, a linear alkyl group of 1 to 6 carbon atoms, an alkyl group branched from 3 to 6 carbon atoms, a cycloalkyl group of 3 to 6 carbon atoms, F, Cl, Br, I, -CF3, -OCF3, -CN, -NO2, -NR5R6, -NHCOR5, -OR5, -SR5, -COOR5, -COR5, and -CH2OH or X and Y define together an ethyleneoxy group of formula -OCH2CH2-, or -CH2CH2O-, or an alkylenedioxy group selected from the group consisting of a methylenedioxy group of formula -OCH2O- and an ethylenedioxy group of formula - OCH2CH2O-, wherein R1 is selected from the group consisting of a linear alkyl group of 1 to 6 carbon atoms, a branched alkyl group of 3 to 6 carbon atoms, a cycloalkylalkyl group having 3 to 6 carbon atoms in the cycloalkyl part thereof and 1 to 3 carbon atoms in the alkyl part thereof, 2-pyridyl-CH2 -, 3-pyridyl and 4-pyridyl CH2--CH2-, wherein R2 is selected from the group consis I H, linear alkyl group of 1 to 6 carbon atoms, a branched alkyl group of 3 to 6 carbon atoms, a cycloalkyl group having 3 to 6 carbon atoms, 2-pyridyl-CH2-, 3-pyridyl- CH2-, 4-pyridyl-CH2-, a benzenesulfonyl group of formula one thiophenesulfonyl group of formula selected from the group of a group of formula ** ** formula one thiophenesulfonyl group of formula ** ** formula group a group of formula * * ** formula and a group of formula R2A-CO-, where R2A is selected in the group consisting of a linear or branched alkyl of 1 to 6 carbon atoms, a cycloalkyl group having 3 to 6 carbon atoms, one cycloalkylalkyl having 3 to 6 carbon atoms in the cycloalkyl part thereof and 1 to 3 carbon atoms in the alkyl part thereof, an alkyloxy group having 1 to 6 carbon atoms, tetrahydro-3-furanyloxy, -CH2OH, -CF3, - CH2CF3, -CH2CH2CF3, piperonyl, pyrrolidinyl, piperidinyl, 4-morpholinyl, CH3O2C-, CH3O2CCH2-, ace ti
