Jonathan Busolli,Nicola Diulgheroff,Moran Pirkes,Alessandro Pontiroli,Marco Villa,Zvi Harel
申请号:
US11893234
公开号:
US08629152B2
申请日:
2007.08.14
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Provided are processes for the preparation of lyophilized pharmaceutically acceptable salts of pemetrexed diacid, in particular, pemetrexed disodium salt, directly from pemetrexed diacid or salts thereof, i.e., without isolating the obtained pemetrexed salt prior to lyophilizing it.