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POLYMERIC COMPOSITIONS OF MONOMETHYL FUMARATE AND THEIR USE IN TREATING RELAPSING REMITTING MULTIPLE SCLEROSIS AND PSORIASIS
专利权人:
DYNAMIC BIOLOGICS INC.
发明人:
Deven Patel,H. Rajan Sharma,Manoj Sharma
申请号:
US16756842
公开号:
US20200237704A1
申请日:
2018.10.16
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention comprises compounds of formula (I): where R1 may be PEG or other polymeric moieties. For example, R1 may be repeating PEG units —;(CH2—;CH2—;O)n—;, wherein n=1-455. R1 may also be other polymeric moieties of varying sizes and structures, for example, R1 may be poly(glycolide), poly(lactic acid), poly(lactide), poly(caprolactone), poly(lactide-co-caprolactone), poly(lactide-co-glycolide), or poly(lactic acid)-butanol. One or more embodiments of the invention may also relate to injectable pharmaceutical compositions comprising polymer conjugated monomethyl fumarate, and methods for treating relapsing-remitting multiple sclerosis and psoriasis.
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来源网址:
http://www.ckcest.cn/home/
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