Compounds with amide groups of biphenyl ethers modified Derivatives of N - ((2 - (cyclohexyloxy or 2H - piran - 2 - iloxi) - 3 '- fluoro [11 '- biphenyl] - 2 - il) - ethyl) - acetamide and 2 - oxo - 2H - cromen 3il - substituted acetamide; compositions and pharmacological inhibitors of hsp90, Hsp70 inducers, useful for treating Neurological Disorders,Associated with diabetic complications such as neuropathy, nephropathy, retinopathy and Vascular Disease. Modified as inhibitors of Hsp90 and Hsp70 inducers (DIV no 3276 - 16)
BLAGG, Brian,DOBROWSKY, Rick T.,ANYIKA, Mercy,BLAGG BRIAN,DOBROWSKY RICK T,ANYIKA MERCY
申请号:
CL2018002367
公开号:
CL2018002367A1
申请日:
2018.08.17
申请国别(地区):
CL
年份:
2018
代理人:
摘要:
Compounds derived from N - ((2 - (cyclohexyloxy or 2H - piran - 2 - iloxi) - 3 '- fluoro [1,1' - biphenyl] - 2 - il) - ethyl) - acetamide and 2 - oxo - 2H - cromen 3il - acetamide, substitutedInhibitors of Hsp90 and Hsp70 inducers; Pharmaceutical Composition and use for treating Neurological Disorders, diabetes, and cancer, among others (Divisional Application 201603276).<;p>;COMPUESTOS DERIVADOS DE N-((2-(CICLOHEXILOXI O 2H-PIRAN-2-ILOXI)-3&rsquo;-FLUORO-[1,1&rsquo;-BIFENIL]-2-IL)-ETIL)-ACETAMIDA Y 2-OXO-2H-CROMEN-3IL-ACETAMIDA SUSTITUIDOS, INHIBIDORES DE HSP90 E INDUCTORES DE HSP70; COMPOSICION FARMACEUTICA; USO PARA TRATAR TRASTORNOS NEUROLOGICOS, DIABETES Y CANCER, ENTRE OTROS (DIVISIONAL SOLICITUD 201603276).<;/p>;