TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.
发明人:
WOLF, IDO,RUBINEK, TAMAR
申请号：
EP13777824
公开号：
EP2844273A4
申请日:
2013.04.16
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
Disclosed are Klotho variant proteins in which residue Glu414 and/or residue Asp238 is substituted with an amino acid different than L-Glu or L-Asp, respectively, as well as polynucleotides encoding the variant proteins, and the use thereof in therapy, especially for the treatment of cancers, especially breast cancer and pancreatic cancer.
