The present invention deal with a process to obtain a decoction from Euterpe oleracea fruits and stones process to obtain a hydro-alcoholic extract from the decoction process to obtain a lyophilized and/or spray dried from the hydro- alcoholic extract pharmaceutical preparations containing the decoction and/or the before mentioned extracts and therapeutic utilization of the preparations in the prevention and treatment of arterial hypertension and other cardiovascular diseases. The extracts induced a significant vasodilator effect in the isolated vascular mesenteric bed of the rats. Capsules and tablets were prepared with the decoctions and lyophilized and or spray dryer of the extracts.