Apparatus for the encapsulation of materials comprises a container (1) which is pre-coated with lipids (2) on an inside surface of the container (1) and has an opening into which a drug (3) in solution can be introduced. The container (1) is then placed in a sonication bath and the lipid (2) which is in solution with the drug (3) forms vesicles under sonication which entrap the drug (3). The encapsulated drug (3) is removed from the container (1) and delivered to the patient shortly after encapsulation.