Omid C. Farokhzad,Frank Alexis,Timothy T. Kuo,Eric Pridgen,Aleksandar Filip Radovic-Moreno,Robert S. Langer
申请号：
US16027121
公开号：
US20180311377A1
申请日:
2018.07.03
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides drug delivery systems comprising FcRn binding partners (e.g., FcRn binding partner, Fc fragment) associated with a particle or an agent to be delivered. Inventive drug delivery systems allow for binding to the FcRn receptor and transcytosis into and/or through a cell or cell layer. Inventive systems are useful for delivering therapeutic agents across the endothelium of blood vessels or the epithelium of an organ.
