SPIROHEPTANE SALICYLAMIDES AND RELATED COMPOUNDS AS INHIBITORS OF ROCK

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专利权人:

BRISTOL-MYERS SQUIBB COMPANY

发明人:

SMITH II, Leon M.,LADZIATA, Vladimir,DELUCCA, Indawati,PINTO, Donald,ORWAT, Michael J.,DILGER, Andrew K.,PABBISETTY, Kumar Balashanmuga,YANG, Wu,SHAW, Scott A.,GLUNZ, Peter W.,PANDA, Manoranjan

申请号：

SG11201805927Y

公开号：

SG11201805927YA

申请日:

2017.01.13

申请国别(地区):

SG

年份:

2018

代理人:

摘要：

or stereoisomers, tautomers, or pharmaceutically-acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.

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