Christopher P. Prior;Andrew J. Turner;David James Ballance;Homayoun Sadeghi
发明人:
David James Ballance,Christopher P. Prior,Homayoun Sadeghi,Andrew J. Turner
申请号:
US12956623
公开号:
US08158579B2
申请日:
2010.11.30
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides fusion proteins comprising an exendin-4 fused to a transferrin (Tf) via a polypeptide linker, as well as corresponding nucleic acid molecules, vectors, host cells, and pharmaceutical compositions. The invention also provides the use of the exendin-4/Tf fusion proteins for treatment of Type II diabetes, obesity, and to reduce body weight.