A needleless fluid injection system including an injection console, an injection chamber in operative communication with the console, an injectate shaft in operative communication with the console, which has an injection lumen extending from a proximal end to a distal end of the shaft, and at least one injection orifice extending through a wall of the injection lumen proximate the distal end of the shaft. The injection lumen can include a sealing cap at its distal end. Alternatively, the system can include an injection plunger having an extending flange portion that is engageable with the console. In another alternative, the system includes an intermediate connector between injection chamber and the injectate shaft. In another embodiment, the system includes a leak management system extending from an outer surface of the injectate shaft.