Vladimir ZARNITSYN,Samirkumar PATEL,Daniel WHITE,Glenn NORONHA,Brian BURKE
申请号:
US15454636
公开号:
US20180028516A1
申请日:
2017.03.09
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Methods and devices are provided for targeted non-surgical administration of a drug formulation to the suprachoroidal space (SCS) of the eye of a human subject for the treatment of a posterior ocular disorder or a choroidal malady. In one embodiment, the method comprises inserting a hollow microneedle into the eye at an insertion site and infusing a drug formulation through the inserted microneedle and into the suprachoroidal space of the eye, wherein the infused drug formulation flows within the suprachoroidal space away from the insertion site during the infusion. In one embodiment, the fluid drug formulation comprises drug nanoparticles or microparticles.