Among other things, there is disclosed a Cranial Electrotherapy Stimulator system. The system includes an electronic unit that produces low-level constant current ranging from 50 μA-500 μA that is delivered to the patient via a pair of conductive electrodes incorporated into ear cushions of a headset with a second independent wireless connection for audio purposes. The CES controls are accomplished via a smart device (phone, tablet, etc.) via a wireless protocol. The smart device contains a dedicated software application (app) that controls operation of the system, allows a user to adjust duration and intensity level of treatment, records treatment parameters (duration, intensity, frequency), presets control and customization of the presets as well as varies level, frequency and waveform shape of the current, gathers patient treatment feedback at the conclusion of each treatment, allows a patient to set up treatment reminders, and allows patient ability to store and share treatment data.