PURPOSE: A composition containing histone diacetylase(HAAC) inhibitors is provided to suppress nasal polyp development .CONSTITUTION: A composition for preventing or treating nasal polyp disorders contains HDAC inhibitors as an active ingredient. The inhibitor is hydroxamic acid, cyclic tetrapeptide, depsipeptide, benzamide, aliphatic acid, nicotine amide, dihydrocoumarin, naphthopyranone, or 2-hydroxynaphaldehydes. A composition for preventing or treating sinusitis contains the inhibitor as an active ingredient.COPYRIGHT KIPO 2012본 발명은 비용종 질환 예방 및/또는 치료용 조성물에 관한 것으로 더욱 상세하게는 히스톤 디아세틸레이즈 저해제를 포함하는 비용종 질환 예방 및/또는 치료용 조성물에 관한 것이다.