Wiley J. Youngs;Matthew J. Panzner;Carolyn L. Cannon
发明人:
Wiley J. Youngs,Matthew J. Panzner,Carolyn L. Cannon
申请号：
US12902807
公开号：
US08648064B2
申请日:
2010.10.12
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention generally relates to metal complexes of N-heterocyclic carbenes that contain one or more additional active moieties and/or groups therein. In one embodiment, the present invention relates to metal complexes of N-heterocyclic carbenes that contain an anti-fungal and/or anti-microbial moiety and/or group in combination with one or more additional active moieties and/or groups selected from fluoroquinolone compounds or derivatives thereof； steroids or derivatives thereof； anti-inflammatory compounds or derivatives thereof； anti-fungal compounds or derivatives thereof； anti-bacterial compounds or derivatives thereof； antagonist compounds or derivatives thereof； H2 receptor compounds or derivatives thereof； chemotherapy compounds or derivatives thereof； tumor suppressor compounds or derivatives thereof； or C1 to C16 alkyl heteroatom groups where the heterotatom is selected from S, O, or N. In still another embodiment, the present invention relates to metal complexes of N-heterocyclic carbenes that contain an anti-fungal and/or anti-microbial moiety and/or group in combination with two or more additional active moieties and/or groups selected from fluoroquinolone compounds or derivatives thereof； steroids or derivatives thereof； anti-inflammatory compounds or derivatives thereof； anti-fungal compounds or derivatives thereof； anti-bacterial compounds or derivatives thereof； antagonist compounds or derivatives thereof； H2 receptor compounds or derivatives thereof； chemotherapy compounds or derivatives thereof； tumor suppressor compounds or derivatives thereof； or C1 to C16 alkyl heteroatom groups where the heterotatom is selected from S, O, or N.
