The present invention provides use of a dragon fruit ovule extract for manufacture of a composition for retarding skin aging. The dragon fruit ovule extract is preferably prepared by extraction of dragon fruit ovule using water as solvent. This extract not only enhances collagen production through promoting skin fibroblast proliferation, but also inhibits collagen glycation, whereby helping to maintain youthful skin.本發明提供一種紅龍果胚珠萃取物用於製備延緩皮膚老化之組合物之用途。該紅龍果胚珠萃取物較佳為以水為溶劑對紅龍果胚珠進行萃取而製得，其能透過促進皮膚纖維母細胞之增生而提升膠原蛋白分泌，亦能減少膠原蛋白醣化終產物生成，因此有助於維持皮膚的年輕狀態。
