Neil Kizer,Nicole M. Bergmann,Gary Gage,Huston Davis Adkisson,Michael Maloney
申请号:
US15501155
公开号:
US20170360989A1
申请日:
2015.07.30
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present disclosure relates to cartilage repair compositions and methods for modifying the proteoglycan content of the compositions. Specifically, the methods relate to serum free, collagen free neocartilage made from chondrocytes that can be used for implants. Proteoglycans, such as aggrecan and sulfated glycosaminoglycan are used and the content modified using temperature changes.