Benjamin Oshlack,Hua-Pin Huang,John Masselink,Alfred P. Tonelli
申请号：
US14673447
公开号：
US20150216810A1
申请日:
2015.03.30
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A solid oral controlled-release oral dosage form of hydrocodone is disclosed. The dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and a sufficient amount of a controlled release material to render the dosage form suitable for twice-a-day administration to a human patient, the dosage form providing a C12/Cmax ratio of 0.55 to 0.85, said dosage form providing a therapeutic effect for at least about 12 hours.
