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MULTIFUNCTIONAL TREATMENT AND DIAGNOSTIC COMPOSITIONS AND METHODS
专利权人:
ZAMADAR; Matibur Rahaman
发明人:
ZAMADAR, Matibur Rahaman
申请号:
SG11202007274U
公开号:
SG11202007274UA
申请日:
2018.03.26
申请国别(地区):
SG
年份:
2020
代理人:
摘要:
Multifunctional compositions and methods are provided for therapeutic treatment of bacteria and cancers and for fluorescence diagnosis. Systems generate in situ reactive oxygen species such as singlet oxygen (1O2), hydroxyl radical (OH) and Juglone, and other chemotherapeutic agents. Methods provided selectively produce greater amounts of one reactive oxygen species over others. Variations are effective in aerobic, anaerobic or H2O2 rich environments and in presence of, or absence of, light. In H2O2 rich environment in absence of light, variations decompose H2O2 into O2 gas to remove excess H2O2 for elimination of hypoxic environment. Variations are formed of porphyrins, naphthalene derivatives, and metal ions, for illustration, free base tetrakis Ar substituted porphyrine core without metal or halide substitution but having hydroxyphenyl and alkyl pyridyl substituents at meso positions combined with dihydroxynaphthalene and +3 hydrated metal ions.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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