Yasumichi Hitoshi,Yonchu Jenkins,Vadim Markovtsov,Todd Kinsella,Tian-Qiang Sun
申请号：
US14498921
公开号：
US20150087673A1
申请日:
2014.09.26
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Disclosed are methods of using AMPK-activating compounds, for example, in the treatment of cancer and disorders of vascular flow. Also disclosed are biomarkers for AMPK and uses thereof, for example, in the diagnosis and treatment of AMPK-linked disorders. In certain embodiments, the AMPK-activating compounds have the structural formulawherein E, J, T, D1, D2, D3, the ring system denoted by “B”, T, R3, R4, w and x are as described herein.
