PROCÉDÉ PERMETTANT DE DÉTECTER LES CELLULES DONT LA MEMBRANE CELLULAIRE EST DÉTÉRIORÉE, LES CELLULES INFECTÉES PAR UN PATHOGÈNE, LES CELLULES MOURANTES ET LES CELLULES MORTES
THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH
发明人:
LAHOUD, MIREILLE HANNA,CAMINSCHI, IRINA,SHORTMAN, KEN,ZHANG, JIAN-GUO,VAN DELFT, MARK FRANCIS,HUANG, DAVID CHING SIANG,WRIGHT, MARK DEXTER
申请号:
EP09745293
公开号:
EP2303407A4
申请日:
2009.05.12
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention relates to methods of modulating the uptake and/or clearance of cells with a disrupted cell membrane, cells infected with a pathogen, dying cells or dead cells, or a portion thereof, which can be used to treat and/or prevent diseases such as cancer, autoimmunity and infections. The present invention also relates to methods of modulating antigen recognition, processing and/or presentation, as well as immune responses to material derived from cells with a disrupted cell membrane, cells infected with a pathogen, dying cells or dead cells, or a portion thereof. The present invention further relates to methods of detecting cells with a disrupted cell membrane, cells infected with a pathogen, dying cells or dead cells, or a portion thereof.