THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
发明人:
CHENG, JIANJUN,GABRIELSON, NATHAN,LICHEN, YIN
申请号：
EP11815380
公开号：
EP2600900A4
申请日:
2011.08.05
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
The invention provides a composition comprising two or more of a) genetic material； b) a condensing agent； c) a membrane destabilizing agent； d) a targeting/stabilizing agent, and optionally e) an ionic cross-linking agent. The components of the composition can self-assemble to form particles via electrostatic and/or lipophilic interactions. Methods of making and using the composition are also provided. The compositions can be used, for example, to transfer genetic material to cells in vitro or in vivo.
