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Dual mechanism inhibitors for the treatment of disease
专利权人:
Mitchell A. deLong;Susan M. Royalty;Jill Marie Sturdivant
发明人:
Mitchell A. deLong,Jill Marie Sturdivant,Susan M. Royalty
申请号:
US12694965
公开号:
US08394826B2
申请日:
2010.01.27
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Provided are compounds that are inhibitors of both rho kinase and of a monoamine transporter (MAT) act to improve the disease state or condition. Further provided are compositions comprising the compounds. Further provided are methods for treating diseases or conditions, the methods comprising administering compounds according to the invention. One such disease may be glaucoma for which, among other beneficial effects, a marked reduction in intraocular pressure (IOP) may be achieved.
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