John R. Desjarlais;Gregory Alan Lazar;Aaron Keith Chamberlain;Bassil I. Dahiyat;Sher Bahadur Karki
发明人:
Aaron Keith Chamberlain,Bassil I. Dahiyat,John R. Desjarlais,Sher Bahadur Karki,Gregory Alan Lazar
申请号:
US12697952
公开号:
US08324351B2
申请日:
2010.02.01
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present application relates to a variant Fc region comprising at least one modification relative to a wild-type human Fc region, where the modification selected from the group consisting of 434S, 252Y/428L, 252Y/434S, and 428L/434S, and the numbering is according to the EU index.