<;P>;PROBLEM TO BE SOLVED: To provide a method of producing an earthworm body fluid and a method of producing an earthworm dried powder which do not improve the rate of clear liquid yield in a centrifuge and filtration process, but also use a spray dryer in a drying process, reduce production processes and work labor, and are excellent in qualities and economy. <;P>;SOLUTION: An earthworm or a crushed earthworm is incubated at 40-60°;C for a temperature-keeping time of 10 min-20 h to promote autodigestion of the earthworm, and a clear earthworm body fluid containing a fibrinolytic active substance is obtained. Then, paste or squeezed juice of a Alliaceae plant, or material in which a nonaqueous material is removed from these materials, is added to the earthworm or the crushed earthworm. Also, the earthworm is mixed into antibacterial sand to be contact treated so that saprophytic bacteria of the body surface and digestive organ of the earthworm are removed. <;P>;COPYRIGHT: (C)2011,JPO&INPIT