Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.本發明描述調節氧化還原酶吲哚胺2,3-雙加氧酶之化合物,及含有該等化合物之組合物。本發明亦提供該等化合物及組合物用於治療及/或預防由吲哚胺2,3-雙加氧酶介導之一系列不同疾病、病症及病狀,包括癌症及免疫相關病症之用途。