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Yeast-brachyury immunotherapeutic compositions
专利权人:
GLOBEIMMUNE INC.;THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
Apelian, David,Guo, Zhimin,Palena, Claudia,Schlom, Jeffrey
申请号:
NZ72479712
公开号:
NZ724797A
申请日:
2012.03.19
申请国别(地区):
NZ
年份:
2020
代理人:
摘要:
Discloses the use of an immunotherapeutic composition comrpising a yeast vehicle, a Brachyury antigen and a further agent selected from the group consisting of an immunotherapeutic virus-based vaccine, a cytokine, a T-cell co-stimulator, a immunomodulator, CD40, anti-CTLA-4 antibody, anti-PD-1, anti-PD-L1, anti-PD-L2 in the manufacture of a medicament for treating cancer. Further discloses a recombinant nucleic acid molecule encoding a fusion protein comprising at least one Brachyury antigen.
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