SUBSTITUIERTE TETRAHYDROISOCHINOLINVERBINDUNGEN ALS GPR120-AGONISTEN

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专利权人:

Merck Sharp & Dohme Corp.

发明人:

ADAMS, Gregory, L.,COX, Jason, M.,DEBENHAM, John, S.,EDMONDSON, Scott,GILBERT, Eric, J.,GUO, Yan,JIANG, Yu,JOSIEN, Hubert,KIM, Hyunjin, M.,LAN, Ping,MIAO, Shouwu,PLUMMER, Christopher, W.,RAJAGOPALAN,

申请号：

EP17803324

公开号：

EP3463362A4

申请日:

2017.05.19

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present invention relates to a compound represented by formula (I) and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing diabetes, hyperlipidemia, obesity, NASH, inflammation related disorders, and related diseases and conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR120. Pharmaceutical compositions and methods of treatment are also included.

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