Nigel Meredith Davies;Ranjeny Thomas;Brendan John O'Sullivan
发明人:
Ranjeny Thomas,Nigel Meredith Davies,Brendan John O'Sullivan,Brendan John OSullivan
申请号:
US12444790
公开号:
US09017697B2
申请日:
2007.10.12
申请国别(地区):
US
年份:
2015
代理人:
摘要:
This invention discloses methods and compositions for modulating immune responses, which involve particulate delivery of agents to immune cells, wherein the agents comprise an inhibitor of the NF-κB signaling pathway and an antigen that corresponds to a target antigen. The methods and compositions of the present invention are particularly useful in the treatment or prophylaxis of an undesirable immune response associated with the target antigen, including autoimmune diseases, allergies and transplantation associated diseases.