UBIQUITIN LIGASE KPC1 PROMOTES PROCESSING OF P105 NF-KAPPAB1 TO P50, ELICITING STRONG TUMOR SUPPRESSION

• 收藏
• 分享

专利权人:

发明人:

Aaron CIECHANOVER,Yevgenia KRAVCHENKO,Inna SHOMER,Victoria COHEN

申请号：

US15544523

公开号：

US20180140667A1

申请日:

2016.01.05

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The invention provides a method for treating cancer comprising the step of administering a therapeutically effective amount of KPC1, a peptide which is at least about 70% homologous to the KPC1 or an agent which up-regulates KPC1. In some embodiments, there is also provided a method for treating cancer comprising the step of administering a therapeutically effective amount of p50, a peptide which is at least about 70% homologous to the p50 or an agent which up-regulates p50.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/