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SELECTIVE ESTROGEN-RECEPTOR MODULATORS (SERMS) CONFER PROTECTION AGAINST PHOTORECEPTOR DEGENERATION
专利权人:
THE UNITED STATES OF AMERICA; as represented by the Secretary; Dept. of Health and Human Service
发明人:
Wenxin Ma,Lian Zhao,Xu Wang,Wai T. Wong
申请号:
US16325678
公开号:
US20190209497A1
申请日:
2017.08.10
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Methods are disclosed for treating and/or preventing retinal degeneration is a subject. In some embodiments, the method includes administering to the subject a therapeutically effective amount of a selective estrogen receptor modulator (SERM) to treat the retinal degeneration in the subject. In other embodiments, the SERM is administered orally. In some examples, the SERM is tamoxifen, afimoxifene, raloxifene, bazedoxifene, arzoxifene, desmethylarzoxifene, or a salt or derivative thereof, or combinations thereof.
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