Thomas D. Aicher,Wai-man Lee,Ronald Jay Hinklin,Mark Joseph Chicarelli,Steven Armen Boyd,Kevin Ronald Condroski
申请号:
US12092233
公开号:
US08933077B2
申请日:
2006.10.24
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Provided are compounds of Formula I wherein R1, R2, Y, Z and G are as defined herein, that are useful in the treatment and/or prevention of diseases mediated by deficient levels of glucokinase activity, such as diabetes mellitus. Also provided are methods of treating or preventing diseases and disorders characterized by underactivity of glucokinase or which can be treated by activating glucokinase.