Alexander Mann,Armin Hatzelmann,Christian Hesslinger,Christof Zitt,Clemens Braun,Degenhard Marx,Dieter Flockerzi,Harold Ohmer,Hermann Tenor,Raimund Külzer,Stefan Fischer,Steffen Weinbrenner,Thomas Mai
申请号:
BR112012014058
公开号:
BR112012014058A2
申请日:
2010.12.15
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
Combination or kits of parts of compounds (1) with therapeutic agnets. The compounds of formula 1, in which A, R1, R2, R3 and R5 have the meanings as given in the description, are novel effective inhibitors of type 4 and 5 phosphodiesterase.