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Compositions comprising sphingosine 1 phosphate (s1p) receptor modulators
专利权人:
Novartis AG
发明人:
Ruegger Colleen,Ambuhl Michael
申请号:
NZ71702208
公开号:
NZ717022A
申请日:
2008.10.09
申请国别(地区):
NZ
年份:
2017
代理人:
摘要:
Discloses herein is a stable binary blend of a pharmaceutical composition for oral administration, which comprises: (i) a compound selected from 2-amino-2-[2-(4-octylphenyl) ethyl]propane-1,3-diol (FTY720, fingolimod) in free form, a pharmaceutically acceptable salt thereof, and (ii) one excipient selected from the group consisting of:microcrystalline cellulose, sodium carboxymethyl starch, hydrogenated castor oil, povidone and pregelatinized starch. This binary blend is suitable for the treatment of organ or tissue transplant rejection, graft versus host disease, autoimmune diseases, inflammatory conditions, viral myocarditis, viral diseases caused by viral myocarditis or cancers.
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