Discloses herein is a stable binary blend of a pharmaceutical composition for oral administration, which comprises: (i) a compound selected from 2-amino-2-[2-(4-octylphenyl) ethyl]propane-1,3-diol (FTY720, fingolimod) in free form, a pharmaceutically acceptable salt thereof, and (ii) one excipient selected from the group consisting of:microcrystalline cellulose, sodium carboxymethyl starch, hydrogenated castor oil, povidone and pregelatinized starch. This binary blend is suitable for the treatment of organ or tissue transplant rejection, graft versus host disease, autoimmune diseases, inflammatory conditions, viral myocarditis, viral diseases caused by viral myocarditis or cancers.