ADRIAN ZÜRCHER,MARC WEHRLI,STEPHAN VON GUNTEN,SYLVIA MIESCHER
申请号:
BR112013014669
公开号:
BR112013014669A2
申请日:
2011.12.14
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The invention relates to the use of CD89 activating molecules, in particular Fc alpha comprising molecules, and more particularly, IgA, for inducing apoptosis in neutrophils. Anti-CD89 antibodies can alternatively be used. The CD89 activation is beneficial in the treatment of various disorders associated with increases in neutrophils, such as autoimmune disorders, inflammatory disorders, NETosis, or cystic fibrosis.