Yury Budansky;Yang Pu;Guichen Tang;Wubao Wang;ROBERT R. ALFANO;Laura Sordillo;James Eastham
发明人:
ROBERT R. ALFANO,Wubao Wang,Yang Pu,Yury Budansky,Laura Sordillo,Guichen Tang,James Eastham
申请号：
US14710222
公开号：
US20150320319A1
申请日:
2015.05.12
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A rectal near infrared (NIR) scanning polarization imaging system uses NIR Photonic Prostatoscopy Analyzer (NIRPPA) for prostate cancer detection using light. The NIRPPA consists of a portable rectal NIR scanning polarization imaging unit and an optical fiber-based rectal probe capable of recording sets of 2D images of a prostate through rectum at different wavelengths and depths and obtaining a three dimensional (3D) image of the prostate and 3D locations of abnormal tissue inside the prostate. Diode lasers/light emission diodes (LEDs) with selected emitting wavelengths are used in the NIR spectral range from 650 nm to 2,400 nm corresponding to the four tissue optical windows (#I, 650 nm-950 nm； #II, 1,100 nm-1,350 nm； #III, 1,600 nm-1,870 nm； and #IV, 2,100 nm-2,300 nm). The fingerprint absorptions of water (H2O), Oxyhemoglobin (HbO2) and deoxyhemoglobin (Hb) in the prostate are used as native biomarkers for prostate cancer detection.
