PEPINSKY BLAKE,RUNKEL LAURA,BRICKELMAIER,WHITTY ADRIAN,HOCHMAN PAULA
申请号：
HU0200444
公开号：
HU229888B1
申请日:
1999.10.15
申请国别(地区):
HU
年份:
2014
代理人:
摘要：
An interferon beta polypeptide comprising interferon-beta 1a coupled to a polymer containing a polyalkylene glycol moiety wherein the interferon-beta-1a and the polyalkylene glycol moiety are arranged such that the interferon-beta-1a has an enhanced activity relative to another therapeutic form of interferon beta (interferon-beta-1b) and exhibits no decrease in activity as compared to non-conjugated interferon-beta-la. The conjugates of the invention are usefully employed in therapeutic as well as non-therapeutic, e.g., diagnostic, applications.
