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HYDROXYALKYL THIADIAZOLE DERIVATIVES
专利权人:
LIMITED;DAIICHI SANKYO COMPANY
发明人:
KHERA, Manoj Kumar,MATHUR, Tarun,SATTIGERI, Jitendra A.,MASUDA, Nobuhisa,SONEDA, Tsuyoshi,KAGOSHIMA, Yoshiko,KONOSU, Toshiyuki,SUZUKI, Tetsuya,YAMAOKA,, Makoto,ITOOKA, Ryo
申请号:
PH12018500697
公开号:
PH12018500697A1
申请日:
2018.03.27
申请国别(地区):
PH
年份:
2018
代理人:
摘要:
Problem to be solved. There is a need for a new antibiotic having a novel mechanism of action, which exhibits strong antibacterial activity not only against sensitive bacteria, but also against resistant bacteria thereof, and at the same time possess excellent solubility and safety profile amenable to human use. Solution to the Problem. As a result of intensive research, the present inventors have found that a compound represented by general formula (I), a stereoisomer, or a pharmaceutically acceptable salt thereof inhibits DNA gyrase GyrB subunit and/or topoisomerase IV ParE subunit, possess excellent solubility and safety profile for use in human for the treatment of bacterial infectious diseases.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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