Pete A. STILES,W. Michael HOOTEN,Mark Daniel SULLIVAN,Patrick H. RUANE,David J. MATLY,Navdeep KAUR,Anubhav ARORA,Ravi PAMNANI
申请号：
US16330111
公开号：
US20190231707A1
申请日:
2017.09.28
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Systems and methods are provided herein for transdermal delivery of an opioid. The opioids can be delivered in a decreasing dose (dose-tapering) manner to minimize withdrawal symptoms and abuse. The systems are also designed to limit a person besides the patient from receiving the drug with the transdermal delivery device. The systems can also include abuse-deterrence features that limit the ability of a patient or unauthorized user from tampering with the device to receive the active ingredient. Novel transdermal drug delivery formulations are also provided that include an opioid agonist or partial agonist and opioid antagonist which prevent the abuse of formulation.
