The medical manipulator includes an arm formed in a tubular shape having a bending portion capable of bending an insertion portion that is formed having channels, with the base end of the arm being connected to the distal end of the insertion portion so that lumens of the arm and the channels are in communication an operation portion for operating the bending portion and transmission members that are capable of advancing and retracting in a longitudinal direction with respect to the insertion portion such that a movement of the operation portion is transmitted to the bending portion and the bending portion is bent and that connect the bending portion and the operation portion an opening portion provided at the operation portion and communicated with the channel and a guide member that guides the movement of the operation portion within a predetermined range and that holds the transmission members to prevent the transmission members from moving in the longitudinal direction with respect to the movement of the operation portion within a portion of the predetermined range.