Steven Do;Zhaoyang Wen;Huiyong Hu;Wendy Lee;Xiaojing Wang;Vickie H. Tsui;Aleksandr Kolesnikov
发明人:
Steven Do,Huiyong Hu,Aleksandr Kolesnikov,Wendy Lee,Vickie H. Tsui,Xiaojing Wang,Zhaoyang Wen
申请号:
US13571595
公开号:
US20130039906A1
申请日:
2012.08.10
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Pyrazolo[3,4-c]pyridine compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, wherein R1 and R2 are as defined herein, are useful for inhibiting Pim kinase, and for treating disorders such as cancer mediated by Pim kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.