Mesenchymal Stem Cells Producing Inhibitory RNA for Disease Modification

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专利权人:

Jan A. Nolta

发明人:

Jan A. Nolta,Scott Olson,Louisa Wirthlin

申请号：

US13260551

公开号：

US20120114618A1

申请日:

2010.03.25

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Compositions and methods for delivering a siRNA, dsRNA, or miRNA polynucleotide into a target cell comprising contacting the target cell with a mesenchymal stem cell, which mesenchymal stem cell comprises an exogenous DNA sequence expressing the siRNA or dsRNA polynucleotide, thereby delivering the siRNA, dsRNA, or miRNA polynucleotide to the target cell through a cellular protrusion or a microvesicle.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/