- Cosmetic composition containing Jeju Wild Ginseng extracts promoting ceramide biosynthesis and having anti-inflammatory effects via activation of Serine-palmitoyl transferase
The present invention relates to a cosmetic composition containing an extract of ginseng and oriental ginseng from Jeju Island as an active ingredient and is useful for promoting ceramide biosynthesis and promoting ceramide-induced dihydroceramide, sphingosine, sphingosine-1-The present invention provides a cosmetic composition exhibiting skin moisturizing, itching improvement and inflammation relieving effects by analyzing the regulating mechanism of ceramide biosynthesis of Jeju island ginseng extract based on metabolism analysis such as phosphate, S1P and glucosylceramide. 본 발명은 제주 산양산삼 추출물을 유효성분으로 함유하는 화장료 조성물에 관한 것으로, 세라마이드 생합성 촉진 및 세라마이드 유래의 디히드로세라마이드(dihydroceramide), 스핑고신(sphingosine), 스핑고신-1-인산염(Sphingosine-1-Phosphate, S1P) 및 글루코실 세라마이드(glucosylceramide) 등 대사체 분석을 기반으로 제주 산양산삼 추출물의 세라마이드 생합성 조절기전을 분석함으로써, 피부 보습, 가려움 개선 및 염증 완화 효과를 발휘하는 화장료 조성물을 제공한다.
