ЭНДРЮС Гэвин П. (GB),ДЖОУНС Дэвид С. (GB),ГОРМАН Шон П. (GB)
申请号：
RU2011113666/15
公开号：
RU2011113666A
申请日:
2009.09.08
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
1. A device containing a housing structure having one or more surfaces, where at least one of the surfaces contains a pH-sensitive layer containing a linear polymer, where the solubility in water of the linear polymer increases from the first solubility in water to the second solubility in water at starting pH. ! 2. The device according to claim 1, where the linear polymer is subjected to dissolution or erosion in an aqueous medium with a second solubility in water. ! 3. A device according to any one of claims 1 and 2, wherein the starting pH is 7 or higher. ! 4. The device according to any one of claims 1 and 2, where the starting pH value is 5.5 or lower. ! 5. The device according to claim 3, where the linear polymer contains one or more bonds of SO, carboxyl groups and sulfate groups. ! 6. The device according to claim 5, where the linear polymer is a methacrylate polymer. ! 7. The device according to claim 4, where the linear polymer contains primary, secondary or tertiary amine groups. ! 8. The device according to claim 7, where the linear polymer contains one or more of dimethylaminomethylmethacrylate and diethylaminoacrylate. ! 9. The device according to any one of claims 1, 2, 5-8 in the form of a catheter, stent, implantable or inserted tube, dental splint or dentures. ! 10. The device according to claim 9 in the form of a urinary tract catheter, a urinary stent, a bile duct stent, a nasogastric tube, a CAPD tube. ! 11. The device according to any one of claims 1, 2, 5-8 or 10, where the pH-sensitive layer contains one or more of buffer groups, antimicrobial compounds, antibiotic compounds, urease inhibitors, EDTA and plasticizing agents. ! 12. The device according to claim 11, where the pH-sensitive layer contains at least one of the following�1. Устройство, содержащее корпусную структуру, имеющую одну или более поверхностей, где, по меньшей мере, одна из поверхностей содержит чувствительный к pH слой, содержащий линейный полимер, где растворимость в воде
