RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY;LAVOIE, EDMOND J.
发明人:
LAVOIE, EDMOND J.,RUCHELMAN, ALEXANDER L.,LIU, LEROY F.
申请号：
CA2510337
公开号：
CA2510337C
申请日:
2003.11.12
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The invention provides compounds of formula I or formula (II), wherein: thebond represented by --- is a single bond or a double bond, and R1-R5, X, and Yhave any of the meanings defined in the specification and theirpharmaceutically acceptable salts. The invention also provides pharmaceuticalcompositions comprising a compound of formula (I or II), processes forpreparing compounds of formula (I or II), intermediates useful for preparingcompounds of formula (I or II), and therapeutic methods for treating cancerand other topoisomerase related conditions using compounds of formula (I orII).
