Institute For Cancer Research d/b/a The Research Institute of Fox Chase Cancer Center
发明人:
BALACHANDRAN, Siddharth,THAPA, Roshan
申请号:
EP17824806
公开号:
EP3481419A4
申请日:
2017.07.05
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
RNA virus vectors comprising a gene encoding the DNA-dependent activator of interferon-regulatory factors (DAI) protein, and optionally further comprising a gene encoding the receptor-interacting serine/threonine-protein kinase 3 (RIPK3) may be used therapeutically to induce cell death, as well as an inflammatory immune response, against tumors and virally-infected cells.