PROBLEM TO BE SOLVED: To provide novel, highly stable compounds having excellent inhibiting activity against plasmid propagation between bacteria, or an excellent antibacterial activity against a broad range of bacteria including drug-resistant bacteria, methods of making them, novel microorganisms that produce the compounds, as well as plasmid propagation inhibitors and antibacterial agents utilizing the compounds.SOLUTION: A plasmid propagation inhibitor comprising at least one of the compounds represented by the structure formulas (1), (2), (3) and (4) is provided.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】細菌間のプラスミド伝播に対する優れた阻害活性、若しくは薬剤耐性菌を含む幅広い細菌に対する優れた抗菌活性を有し、安定性の高い新規化合物、その製造方法、その生産菌である新規微生物、それを利用したプラスミド伝播阻害剤及び抗菌剤の提供。【解決手段】構造式(1)、(2)、(3)、及び(4)で表される化合物の少なくともいずれかを含むプラスミド伝播阻害剤。【選択図】なし