Regeneron Pharmaceuticals, Inc.; Inc.;Institute for Research in Biomedicine (IRB);Yale University;Regeneron Pharmaceuticals
发明人:
Murphy, Andrew J.,Stevens, Sean,Flavell, Richard,Manz, Markus,Shan, Liang
申请号：
AU2015264427
公开号：
AU2015264427A1
申请日:
2015.05.18
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
Genetically modified non-human animals expressing human EPO from the animal genome are provided. Also provided are methods for making non-human animals expressing human EPO from the non-human animal genome, and methods for using non-human animals expressing human EPO from the non-human animal genome. These animals and methods find many uses in the art, including, for example, in modeling human erythropoiesis and erythrocyte function； in modeling human pathogen infection of erythrocytes； in
