The invention relates to a nutritional composition comprising (a) at least 18 en% of proteinaceous matter, said proteinaceous matter comprising whey； (b) at least 12 wt% of leucine, based on total proteinaceous matter； and (c) a lipid fraction comprising at least a É-3 polyunsaturated fatty acid selected from the group of eicosapentaenoic acid, docosahexaenoic acid, eicosatetraenoic acid and docosapentaenoic acid for improving the muscle function in a mammal, for improving daily activity, for improving physical performance, for providing a better prognosis in terms of extended life-expectancy, for improving compliance to an anti-cancer therapy or for improving a quality of life.
