An improved drug delivery composition and method of use is disclosed.The composition comprises one or more biodegradable block copolymer drugcarriers; and a reconstitution enhancing and enabling agent comprisingpolyethyleneglycol (PEG), a PEG derivative or a mixture of PEG and a PEG derivative. Thecomposition can be administered as is or after being be dissolved or rapidlyreconstituted in an aqueous vehicle to afford a homogeneous solution oruniformcolloidal system.